Establishment of an erythroid cell line from primary CD36+ erythroid progenitor cells
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چکیده
منابع مشابه
Development of Erythroid Progenitor Cells
Erythropoietin (EP), insulin-like growth factor I (IGF-I) and stem cell factor (SCF) each reduce apoptosis of human erythroid progenitor cells. To determine if these growth factors have additional roles in stimulating erythropoiesis, the proliferation, maturation, and survival of highly purified human erythroid colony-forming cells (ECFCs) were studied during the application of different combin...
متن کاملEstablishment of Immortalized Human Erythroid Progenitor Cell Lines Able to Produce Enucleated Red Blood Cells
Transfusion of red blood cells (RBCs) is a standard and indispensable therapy in current clinical practice. In vitro production of RBCs offers a potential means to overcome a shortage of transfusable RBCs in some clinical situations and also to provide a source of cells free from possible infection or contamination by microorganisms. Thus, in vitro production of RBCs may become a standard proce...
متن کاملHuman erythroid progenitor cells express Rhesus antigens.
The expression of Rhesus antigens on hematopoietic progenitor cells was studied using monoclonal antibodies. Because these antibodies are not capable of lysing mature red blood cells in a complement-dependent cytotoxicity assay, fluorescence-activated cell sorting was performed. Using the monoclonal anti-Rh 29 antibody B10, 68% +/- 6% of the mature erythroid progenitor cells (CFU-E) were sorted...
متن کاملAbnormal erythroid progenitor cells in human preleukemia.
Ten patients with preleukemia were studied by the erythroid cell clonal culture technique. In nine of these patients, erythroid colonies derived from peripheral blood BFU-E were not observed, while the other patient had markedly decreased peripheral blood BFU-E-derived erythroid colonies in vitro. In three patients, marrow cells were also cultured and no BFU-E-derived erythroid colonies were de...
متن کاملErythroid Progenitor-derived Colonies
Address reprint requests to Dr. David G. Nathan, Children's Hospital Medical Center, Boston, MA 02115. Received for publication 6 April 1982 and in revised form 12 July 1982. in environmental erythropoietin and burst-promoting activities.
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ژورنال
عنوان ژورنال: Experimental Hematology
سال: 2010
ISSN: 0301-472X
DOI: 10.1016/j.exphem.2010.07.012